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Determination of amyloid core regions of insulin analogues fibrils

A rapid-acting insulin lispro and long-acting insulin glargine are commonly used for the treatment of diabetes. Clinical cases have described the formation of injectable amyloidosis with these insulin analogues, but their amyloid core regions of fibrils were unknown. To reveal these regions, we have...

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Vydáno v:Prion
Hlavní autoři: Surin, Alexey K., Grishin, Sergei Yu., Galzitskaya, Oxana V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518739/
https://ncbi.nlm.nih.gov/pubmed/32543316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2020.1776062
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