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Determination of amyloid core regions of insulin analogues fibrils

A rapid-acting insulin lispro and long-acting insulin glargine are commonly used for the treatment of diabetes. Clinical cases have described the formation of injectable amyloidosis with these insulin analogues, but their amyloid core regions of fibrils were unknown. To reveal these regions, we have...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Surin, Alexey K., Grishin, Sergei Yu., Galzitskaya, Oxana V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518739/
https://ncbi.nlm.nih.gov/pubmed/32543316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2020.1776062
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