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Cyclosporine Broadens the Therapeutic Potential of Lenalidomide in Myeloid Malignancies
The immunomodulatory drug lenalidomide is used for the treatment of certain hematologic malignancies, including myelodysplastic syndromes (MDS). Lenalidomide interacts with cereblon (CRBN), a component of the CRL4(CRBN) E3 ubiquitin ligase complex, leading to ubiquitination and subsequent degradatio...
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| Publicat a: | J Cell Immunol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7518522/ https://ncbi.nlm.nih.gov/pubmed/32984863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/immunology.2.049 |
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