Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro

Our previous study revealed that expression of G protein-coupled receptor 68 (GPR68) was upregulated in MDSL cells, a cell line representing Myelodysplastic Syndromes (MDS), in response to lenalidomide (LEN), and mediated a calcium/calpain proapoptotic pathway. Isx, a GPR68 agonist, enhanced the sen...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: He, Xiaofei, Dou, Aixia, Feng, Saran, Roman-Rivera, Ashley, Hawkins, Caleb, Lawley, Lauren, Zhang, Jiajia, Wunderlich, Mark, Mizukawa, Benjamin, Halene, Stephanie, Patel, Amisha, Fang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335335/
https://ncbi.nlm.nih.gov/pubmed/32437909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.05.001
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