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Dihydropyrimidine Dehydrogenase Deficiency: To Screen or Not to Screen?
5-fluorouracil (5-FU) and its prodrug capecitabine are frequently prescribed in oncology. While usually well tolerated, toxicity can be severe, and even life-threatening. A dihydropyrimidine dehydrogenase (DPD) deficiency can cause severe toxicity. Current testing for DPD deficiency does not meet th...
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| Publicado no: | J Adv Pract Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Harborside Press LLC
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7517765/ https://ncbi.nlm.nih.gov/pubmed/33542850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6004/jadpro.2020.11.1.4 |
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