Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction

BACKGROUND: Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation. Dopamine (DA) concentrations and tyrosine hydroxylase (T...

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Опубликовано в: :BMC Vet Res
Главные авторы: Fortin, Jessica S., Benskey, Matthew J., Lookingland, Keith J., Patterson, Jon S., Howey, Erin B., Goudreau, John L., Schott, Harold C.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517620/
https://ncbi.nlm.nih.gov/pubmed/32977825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02565-3
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