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Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction

BACKGROUND: Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation. Dopamine (DA) concentrations and tyrosine hydroxylase (T...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Fortin, Jessica S., Benskey, Matthew J., Lookingland, Keith J., Patterson, Jon S., Howey, Erin B., Goudreau, John L., Schott, Harold C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517620/
https://ncbi.nlm.nih.gov/pubmed/32977825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02565-3
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