Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction

BACKGROUND: Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation. Dopamine (DA) concentrations and tyrosine hydroxylase (T...

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Veröffentlicht in:BMC Vet Res
Hauptverfasser: Fortin, Jessica S., Benskey, Matthew J., Lookingland, Keith J., Patterson, Jon S., Howey, Erin B., Goudreau, John L., Schott, Harold C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517620/
https://ncbi.nlm.nih.gov/pubmed/32977825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02565-3
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