Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction

BACKGROUND: Pituitary pars intermedia dysfunction (PPID) develops slowly in aged horses as degeneration of hypothalamic dopaminergic neurons leads to proliferation of pars intermedia (PI) melanotropes through hyperplasia and adenoma formation. Dopamine (DA) concentrations and tyrosine hydroxylase (T...

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Vydáno v:BMC Vet Res
Hlavní autoři: Fortin, Jessica S., Benskey, Matthew J., Lookingland, Keith J., Patterson, Jon S., Howey, Erin B., Goudreau, John L., Schott, Harold C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517620/
https://ncbi.nlm.nih.gov/pubmed/32977825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02565-3
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