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Targeting the Mutational Landscape of Bystander Cells: Drug-Promoted Blood Cancer From High-Prevalence Pre-neoplasias in Patients on BRAF Inhibitors

Drug-promoted cancers are increasingly recognized as a serious clinical problem in patients receiving BRAF inhibitory treatment. Here we report on a patient with BRAF mutant hairy cell leukemia and monoclonal B-cell lymphocytosis (MBL), who responded durably to BRAF/MEK inhibitors (BRAFi/MEKi) but e...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Simnica, Donjete, Ittrich, Harald, Bockemeyer, Carsten, Stein, Alexander, Binder, Mascha
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517330/
https://ncbi.nlm.nih.gov/pubmed/33042833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.540030
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