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BRAF and MEK Inhibitors: Use and Resistance in BRAF-Mutated Cancers

The mitogen activated protein kinase/extracellular signal-related kinase (MAPK/ERK) signaling pathway serves an integral role in growth, proliferation, differentiation, migration, and survival of all mammalian cells. Aberrant signaling of this pathway is often observed in several types of hematologi...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Sanchez, Jaquelyn N., Wang, Ton, Cohen, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080616/
https://ncbi.nlm.nih.gov/pubmed/29488071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-018-0884-8
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