Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma

PURPOSE: Glioblastoma is an aggressive and molecularly heterogeneous cancer with few effective treatment options. We hypothesized that next-generation sequencing can be used to guide treatment recommendations within a clinically acceptable time frame following surgery for patients with recurrent gli...

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Udgivet i:Clin Cancer Res
Main Authors: Byron, Sara A., Tran, Nhan L., Halperin, Rebecca F., Phillips, Joanna J., Kuhn, John G., de Groot, John F., Colman, Howard, Ligon, Keith L., Wen, Patrick Y., Cloughesy, Timothy F., Mellinghoff, Ingo K., Butowski, Nicholas A., Taylor, Jennie W., Clarke, Jennifer L., Chang, Susan M., Berger, Mitchel S., Molinaro, Annette M., Maggiora, Gerald M., Peng, Sen, Nasser, Sara, Liang, Winnie S., Trent, Jeffrey M., Berens, Michael E., Carpten, John D., Craig, David W., Prados, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516926/
https://ncbi.nlm.nih.gov/pubmed/29074604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0963
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