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Clinical translation of (18)F-fluoropivalate – a PET tracer for imaging short-chain fatty acid metabolism: safety, biodistribution, and dosimetry in fed and fasted healthy volunteers
BACKGROUND: Fatty acids derived de novo or taken up from the extracellular space are an essential source of nutrient for cell growth and proliferation. Radiopharmaceuticals including (11)C-acetate, and (18)F-FAC (2-(18)F-fluoroacetate), have previously been used to study short-chain fatty acid (SCFA...
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| Publicado no: | Eur J Nucl Med Mol Imaging |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7515955/ https://ncbi.nlm.nih.gov/pubmed/32123971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-04724-y |
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