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A phase I, randomized, single-dose pharmacokinetic study comparing sb8 (bevacizumab biosimilar) with reference bevacizumab in healthy volunteers

PURPOSE: To compare pharmacokinetics, safety, tolerability, and immunogenicity between SB8, a bevacizumab biosimilar, and the European Union (EU) and United States (US) reference products (bevacizumab-EU, bevacizumab-US). METHODS: In this randomized, double-blind, parallel-group, and single-dose stu...

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Dettagli Bibliografici
Pubblicato in:Cancer Chemother Pharmacol
Autori principali: Shin, Donghoon, Lee, Yoon Jung, Choi, Jihye, Lee, Dahyoung, Park, Minjeong, Petkova, Magdalena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515939/
https://ncbi.nlm.nih.gov/pubmed/32949267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04144-7
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