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Comparative pharmacokinetics of an adalimumab biosimilar SB5 administered via autoinjector or prefilled syringe in healthy subjects

PURPOSE: The objective of this study was to demonstrate comparable pharmacokinetic (PK), safety, and tolerability parameters of the adalimumab biosimilar SB5 administered via autoinjector (AI) pen or prefilled syringe (PFS). PATIENTS AND METHODS: In this phase 1, randomized, open-label, single-dose,...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: Shin, Donghoon, Lee, Younju, Jeong, Deokyoon, Ellis-Pegler, Rod
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225915/
https://ncbi.nlm.nih.gov/pubmed/30464411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169082
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