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Comparative pharmacokinetics of an adalimumab biosimilar SB5 administered via autoinjector or prefilled syringe in healthy subjects

PURPOSE: The objective of this study was to demonstrate comparable pharmacokinetic (PK), safety, and tolerability parameters of the adalimumab biosimilar SB5 administered via autoinjector (AI) pen or prefilled syringe (PFS). PATIENTS AND METHODS: In this phase 1, randomized, open-label, single-dose,...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Shin, Donghoon, Lee, Younju, Jeong, Deokyoon, Ellis-Pegler, Rod
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225915/
https://ncbi.nlm.nih.gov/pubmed/30464411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169082
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