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Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions

From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects. Using statistical mechanical modelling, we describe here how multivalency can be exploited to achieve what we dub range selectivity, that is, b...

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Publicat a:Nat Commun
Autors principals: Liu, Meng, Apriceno, Azzurra, Sipin, Miguel, Scarpa, Edoardo, Rodriguez-Arco, Laura, Poma, Alessandro, Marchello, Gabriele, Battaglia, Giuseppe, Angioletti-Uberti, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515919/
https://ncbi.nlm.nih.gov/pubmed/32973157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18603-5
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