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Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions

From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects. Using statistical mechanical modelling, we describe here how multivalency can be exploited to achieve what we dub range selectivity, that is, b...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Meng, Apriceno, Azzurra, Sipin, Miguel, Scarpa, Edoardo, Rodriguez-Arco, Laura, Poma, Alessandro, Marchello, Gabriele, Battaglia, Giuseppe, Angioletti-Uberti, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515919/
https://ncbi.nlm.nih.gov/pubmed/32973157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18603-5
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