Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1

Pancreatic cancer is one of the most fatal cancers without druggable molecular targets. Hypoxia inducible factor-1 (HIF-1) is a heterodimeric transcriptional factor that promotes malignancy in various cancers including pancreatic cancer. Herein, we found that HIF-1 is accumulated in normoxic or mode...

Full description

Saved in:
Bibliographic Details
Published in:Oncogene
Main Authors: Kanamori, Akane, Matsubara, Daisuke, Saitoh, Yurika, Fukui, Yuya, Gotoh, Noriko, Kaneko, Shuichi, Seiki, Motoharu, Murakami, Yoshinori, Inoue, Jun-ichiro, Sakamoto, Takeharu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515798/
https://ncbi.nlm.nih.gov/pubmed/32826949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01423-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items