Mint3 Enhances the Activity of Hypoxia-inducible Factor-1 (HIF-1) in Macrophages by Suppressing the Activity of Factor Inhibiting HIF-1

Por Sakamoto, Takeharu, Seiki, Motoharu
Publicado em 2009

A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism

Por Sakamoto, Takeharu, Seiki, Motoharu
Publicado em 2010

Integrated functions of membrane‐type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase

Por Sakamoto, Takeharu, Seiki, Motoharu
Publicado no Cancer Sci (2017)

Targeting the Warburg Effect That Arises in Tumor Cells Expressing Membrane Type-1 Matrix Metalloproteinase

Por Sakamoto, Takeharu, Niiya, Daigo, Seiki, Motoharu
Publicado em 2011

ZF21 Protein Regulates Cell Adhesion and Motility

Por Nagano, Makoto, Hoshino, Daisuke, Sakamoto, Takeharu, Kawasaki, Noritaka, Koshikawa, Naohiko, Seiki, Motoharu
Publicado em 2010

ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center

Por Nagano, Makoto, Hoshino, Daisuke, Sakamoto, Takeharu, Akizawa, Toshifumi, Koshikawa, Naohiko, Seiki, Motoharu
Publicado em 2011

Deletion of the Mint3/Apba3 Gene in Mice Abrogates Macrophage Functions and Increases Resistance to Lipopolysaccharide-induced Septic Shock

Por Hara, Toshiro, Mimura, Kouhei, Abe, Takaya, Shioi, Go, Seiki, Motoharu, Sakamoto, Takeharu
Publicado em 2011

Genetic Screening of New Genes Responsible for Cellular Adaptation to Hypoxia Using a Genome-Wide shRNA Library

Por Yoshino, Seiko, Hara, Toshiro, Weng, Jane S., Takahashi, Yuka, Seiki, Motoharu, Sakamoto, Takeharu
Publicado em 2012

Hypoxia-Inducible Factor 1 Regulation through Cross Talk between mTOR and MT1-MMP

Por Sakamoto, Takeharu, Weng, Jane S., Hara, Toshiro, Yoshino, Seiko, Kozuka-Hata, Hiroko, Oyama, Masaaki, Seiki, Motoharu
Publicado em 2014

The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux

Por Yoshino, Seiko, Hara, Toshiro, Nakaoka, Hiroki J, Kanamori, Akane, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Publicado no Cell Discov (2016)

Identification and Characterization of Lutheran Blood Group Glycoprotein as a New Substrate of Membrane-type 1 Matrix Metalloproteinase 1 (MT1-MMP): A SYSTEMIC WHOLE CELL ANALYSIS...

Por Niiya, Daigo, Egawa, Nagayasu, Sakamoto, Takeharu, Kikkawa, Yamato, Shinkawa, Takashi, Isobe, Toshiaki, Koshikawa, Naohiko, Seiki, Motoharu
Publicado em 2009

Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus

Por Uematsu, Takayuki, Fujita, Tomoko, Nakaoka, Hiroki J., Hara, Toshiro, Kobayashi, Noritada, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Publicado no Sci Rep (2016)

Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer

Por Temma, Takashi, Hanaoka, Hirofumi, Yonezawa, Aki, Kondo, Naoya, Sano, Kohei, Sakamoto, Takeharu, Seiki, Motoharu, Ono, Masahiro, Saji, Hideo
Publicado em 2014

Mint3 potentiates TLR3/4- and RIG-I–induced IFN-β expression and antiviral immune responses

Por Huai, Wanwan, Song, Hui, Yu, Zhongxia, Wang, Wenwen, Han, Lihui, Sakamoto, Takeharu, Seiki, Motoharu, Zhang, Lining, Zhang, Qunye, Zhao, Wei
Publicado no Proc Natl Acad Sci U S A (2016)

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells

Por Nakaoka, Hiroki J., Hara, Toshiro, Yoshino, Seiko, Kanamori, Akane, Matsui, Yusuke, Shimamura, Teppei, Sato, Hiroshi, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Publicado no Sci Rep (2016)

Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes

Por Hara, Toshiro, Nakaoka, Hiroki J., Hayashi, Tetsuro, Mimura, Kouhei, Hoshino, Daisuke, Inoue, Masahiro, Nagamura, Fumitaka, Murakami, Yoshinori, Seiki, Motoharu, Sakamoto, Takeharu
Publicado no Proc Natl Acad Sci U S A (2017)

Novel adherent CD11b(+) Gr-1(+) tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment

Por Tsubaki, Takuya, Kadonosono, Tetsuya, Sakurai, Shimon, Shiozawa, Tadashi, Goto, Toshiki, Sakai, Shiori, Kuchimaru, Takahiro, Sakamoto, Takeharu, Watanabe, Hitomi, Kondoh, Gen, Kizaka-Kondoh, Shinae
Publicado no Oncotarget (2018)