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Mint3 potentiates TLR3/4- and RIG-I–induced IFN-β expression and antiviral immune responses

Type I IFNs (IFN-α/β) play crucial roles in the elimination of invading viruses. Multiple immune cells including macrophages recognize viral infection through a variety of pattern recognition receptors, such as Toll-like receptors (TLRs) and retinoic acid-inducible gene-I (RIG-I)–like receptors, and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huai, Wanwan, Song, Hui, Yu, Zhongxia, Wang, Wenwen, Han, Lihui, Sakamoto, Takeharu, Seiki, Motoharu, Zhang, Lining, Zhang, Qunye, Zhao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081575/
https://ncbi.nlm.nih.gov/pubmed/27698125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601556113
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