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Investigation of a MMP-2 Activity-Dependent Anchoring Probe for Nuclear Imaging of Cancer
PURPOSE: Since matrix metalloproteinase-2 (MMP-2) is an important marker of tumor malignancy, we developed an original drug design strategy, MMP-2 activity dependent anchoring probes (MDAP), for use in MMP-2 activity imaging, and evaluated the usefulness of this probe in in vitro and in vivo experim...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092090/ https://ncbi.nlm.nih.gov/pubmed/25010662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102180 |
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