The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair

Nucleotide excision repair (NER) is an essential pathway to remove bulky lesions affecting one strand of DNA. Defects in components of this repair system are at the ground of genetic diseases such as xeroderma pigmentosum (XP) and Cockayne syndrome (CS). The XP complementation group G (XPG) endonucl...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: González-Corrochano, Rocío, Ruiz, Federico M, Taylor, Nicholas M I, Huecas, Sonia, Drakulic, Srdja, Spínola-Amilibia, Mercedes, Fernández-Tornero, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515719/
https://ncbi.nlm.nih.gov/pubmed/32821917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa688
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