The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair

Nucleotide excision repair (NER) is an essential pathway to remove bulky lesions affecting one strand of DNA. Defects in components of this repair system are at the ground of genetic diseases such as xeroderma pigmentosum (XP) and Cockayne syndrome (CS). The XP complementation group G (XPG) endonucl...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: González-Corrochano, Rocío, Ruiz, Federico M, Taylor, Nicholas M I, Huecas, Sonia, Drakulic, Srdja, Spínola-Amilibia, Mercedes, Fernández-Tornero, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515719/
https://ncbi.nlm.nih.gov/pubmed/32821917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa688
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