The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair

Nucleotide excision repair (NER) is an essential pathway to remove bulky lesions affecting one strand of DNA. Defects in components of this repair system are at the ground of genetic diseases such as xeroderma pigmentosum (XP) and Cockayne syndrome (CS). The XP complementation group G (XPG) endonucl...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: González-Corrochano, Rocío, Ruiz, Federico M, Taylor, Nicholas M I, Huecas, Sonia, Drakulic, Srdja, Spínola-Amilibia, Mercedes, Fernández-Tornero, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515719/
https://ncbi.nlm.nih.gov/pubmed/32821917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa688
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