The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair

Nucleotide excision repair (NER) is an essential pathway to remove bulky lesions affecting one strand of DNA. Defects in components of this repair system are at the ground of genetic diseases such as xeroderma pigmentosum (XP) and Cockayne syndrome (CS). The XP complementation group G (XPG) endonucl...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: González-Corrochano, Rocío, Ruiz, Federico M, Taylor, Nicholas M I, Huecas, Sonia, Drakulic, Srdja, Spínola-Amilibia, Mercedes, Fernández-Tornero, Carlos
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515719/
https://ncbi.nlm.nih.gov/pubmed/32821917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa688
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