Clinical implication and usefulness of de novo EGFR T790M mutation in lung adenocarcinoma with EGFR-tyrosine kinase inhibitor sensitizing mutation

Detection rate of de novo EGFR T790 M mutation was increased up to 80% through recent ultrasensitive detection methods. Here, we investigated the clinical significance and its usefulness of detecting de novo EGFR T790 M using ultrasensitive droplet-digital polymerase chain reaction (ddPCR) method. I...

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Publicado en:Cancer Biol Ther
Autores principales: Lee, Sang Hoon, Kim, Eun Young, Kim, Arum, Chang, Yoon Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515544/
https://ncbi.nlm.nih.gov/pubmed/32543264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1776579
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