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Clinical implication and usefulness of de novo EGFR T790M mutation in lung adenocarcinoma with EGFR-tyrosine kinase inhibitor sensitizing mutation

Detection rate of de novo EGFR T790 M mutation was increased up to 80% through recent ultrasensitive detection methods. Here, we investigated the clinical significance and its usefulness of detecting de novo EGFR T790 M using ultrasensitive droplet-digital polymerase chain reaction (ddPCR) method. I...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Lee, Sang Hoon, Kim, Eun Young, Kim, Arum, Chang, Yoon Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515544/
https://ncbi.nlm.nih.gov/pubmed/32543264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1776579
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