Lataa...
Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity
Most sporadic colorectal cancer reflects acquired mutations in the adenomatous polyposis coli (APC) tumor suppressor gene, while germline heterozygosity for mutant APC produces the autosomal dominant disorder Familial Adenomatous Polyposis (FAP) with a predisposition to colorectal cancer. In these s...
Tallennettuna:
| Julkaisussa: | Cancer Biol Ther |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2020
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7515455/ https://ncbi.nlm.nih.gov/pubmed/32594830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1779005 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|