ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity

The activity of Thioredoxin-1 (Trx-1) is adjusted by the balance of its monomeric, active and its dimeric, inactive state. The regulation of this balance is not completely understood. We have previously shown that the cytoplasmic domain of the transmembrane protein A Disintegrin And Metalloprotease...

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Publicado en:Redox Biol
Autores principales: e Costa, Rute A.P., Granato, Daniela C., Trino, Luciana D., Yokoo, Sami, Carnielli, Carolina M., Kawahara, Rebeca, Domingues, Romênia R., Pauletti, Bianca Alves, Neves, Leandro Xavier, Santana, Aline G., Paulo, Joao A., Aragão, Annelize Z.B., Heleno Batista, Fernanda Aparecida, Migliorini Figueira, Ana Carolina, Laurindo, Francisco R.M., Fernandes, Denise, Hansen, Hinrich P., Squina, Fabio, Gygi, Steven P., Paes Leme, Adriana F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513893/
https://ncbi.nlm.nih.gov/pubmed/33011677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101735
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