ADAM17 mediates OSCC development in an orthotopic murine model

BACKGROUND: ADAM17 is one of the main sheddases of the cells and it is responsible for the cleavage and the release of ectodomains of important signaling molecules, such as EGFR ligands. Despite the known crosstalk between ADAM17 and EGFR, which has been considered a promising targeted therapy in or...

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Detalhes bibliográficos
Main Authors: Simabuco, Fernando Moreira, Kawahara, Rebeca, Yokoo, Sami, Granato, Daniela C, Miguel, Lucas, Agostini, Michelle, Aragão, Annelize ZB, Domingues, Romênia R, Flores, Isadora L, Macedo, Carolina CS, Coletta, Ricardo Della, Graner, Edgard, Paes Leme, Adriana Franco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928084/
https://ncbi.nlm.nih.gov/pubmed/24495306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-24
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