ADAM17 mediates OSCC development in an orthotopic murine model

BACKGROUND: ADAM17 is one of the main sheddases of the cells and it is responsible for the cleavage and the release of ectodomains of important signaling molecules, such as EGFR ligands. Despite the known crosstalk between ADAM17 and EGFR, which has been considered a promising targeted therapy in or...

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保存先:
書誌詳細
主要な著者: Simabuco, Fernando Moreira, Kawahara, Rebeca, Yokoo, Sami, Granato, Daniela C, Miguel, Lucas, Agostini, Michelle, Aragão, Annelize ZB, Domingues, Romênia R, Flores, Isadora L, Macedo, Carolina CS, Coletta, Ricardo Della, Graner, Edgard, Paes Leme, Adriana Franco
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2014
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928084/
https://ncbi.nlm.nih.gov/pubmed/24495306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-24
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