ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity

The activity of Thioredoxin-1 (Trx-1) is adjusted by the balance of its monomeric, active and its dimeric, inactive state. The regulation of this balance is not completely understood. We have previously shown that the cytoplasmic domain of the transmembrane protein A Disintegrin And Metalloprotease...

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Veröffentlicht in:Redox Biol
Hauptverfasser: e Costa, Rute A.P., Granato, Daniela C., Trino, Luciana D., Yokoo, Sami, Carnielli, Carolina M., Kawahara, Rebeca, Domingues, Romênia R., Pauletti, Bianca Alves, Neves, Leandro Xavier, Santana, Aline G., Paulo, Joao A., Aragão, Annelize Z.B., Heleno Batista, Fernanda Aparecida, Migliorini Figueira, Ana Carolina, Laurindo, Francisco R.M., Fernandes, Denise, Hansen, Hinrich P., Squina, Fabio, Gygi, Steven P., Paes Leme, Adriana F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513893/
https://ncbi.nlm.nih.gov/pubmed/33011677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101735
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