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Growth-factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Precise control and maintenance of population size is fundamental for organismal development and homeostasis. The three cell types of the mammalian blastocyst are generated in precise proportions over a short time, suggesting a mechanism to ensure a reproducible outcome. We developed a minimal mathe...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Saiz, Néstor, Mora-Bitria, Laura, Rahman, Shahadat, George, Hannah, Herder, Jeremy P, Garcia-Ojalvo, Jordi, Hadjantonakis, Anna-Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513828/
https://ncbi.nlm.nih.gov/pubmed/32720894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56079
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