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Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide
The synthesis and biological activity of 42 novel S-lipidated analogues of a connexin 43 channel inhibitory Peptide5 is described. Unmodified Peptide5 moderates hemichannels and gap junctions that are both implicated in the progression of neurological disease. Peptide5 was site-specifically modified...
Tallennettuna:
| Julkaisussa: | RSC Med Chem |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Royal Society of Chemistry
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7513673/ https://ncbi.nlm.nih.gov/pubmed/33479696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00172d |
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