Cerebrospinal Fluid YKL-40 and Chitotriosidase Levels in Frontotemporal Dementia Vary by Clinical, Genetic and Pathological Subtype

BACKGROUND: Chronic glial dysfunction may contribute to the pathogenesis of frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) levels of glia-derived proteins YKL-40 and chitotriosidase are increased in Alzheimer's disease (AD) but have not been explored in detail across the spectrum of F...

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Udgivet i:Dement Geriatr Cogn Disord
Main Authors: Woollacott, Ione O.C., Nicholas, Jennifer M., Heller, Carolin, Foiani, Martha S., Moore, Katrina M., Russell, Lucy L., Paterson, Ross W., Keshavan, Ashvini, Schott, Jonathan M., Warren, Jason D., Heslegrave, Amanda, Zetterberg, Henrik, Rohrer, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513620/
https://ncbi.nlm.nih.gov/pubmed/32344399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000506282
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