CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

BACKGROUND: Increased CSF levels of a number of synaptic markers have been reported in Alzheimer’s disease (AD), but little is known about their concentrations in frontotemporal dementia (FTD). We investigated this in three synaptic proteins, neurogranin, SNAP-25, and synaptotagmin-1. METHODS: CSF s...

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發表在:Alzheimers Res Ther
Main Authors: Clarke, Mica T. M., Brinkmalm, Ann, Foiani, Martha S., Woollacott, Ione O. C., Heller, Carolin, Heslegrave, Amanda, Keshavan, Ashvini, Fox, Nick C., Schott, Jonathan M., Warren, Jason D., Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918699/
https://ncbi.nlm.nih.gov/pubmed/31847891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0564-2
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