CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

BACKGROUND: Increased CSF levels of a number of synaptic markers have been reported in Alzheimer’s disease (AD), but little is known about their concentrations in frontotemporal dementia (FTD). We investigated this in three synaptic proteins, neurogranin, SNAP-25, and synaptotagmin-1. METHODS: CSF s...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Clarke, Mica T. M., Brinkmalm, Ann, Foiani, Martha S., Woollacott, Ione O. C., Heller, Carolin, Heslegrave, Amanda, Keshavan, Ashvini, Fox, Nick C., Schott, Jonathan M., Warren, Jason D., Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918699/
https://ncbi.nlm.nih.gov/pubmed/31847891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0564-2
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