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Stability of blood-based biomarkers of Alzheimer's disease over multiple freeze-thaw cycles

INTRODUCTION: Freeze-thaw instability may contribute to preanalytical variation in blood-based biomarker studies. We investigated the effects of up to four freeze-thaw cycles on single molecule array immunoassays of serum neurofilament light chain and plasma total tau, amyloid β 1–40 (Aß(40)), and A...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Keshavan, Ashvini, Heslegrave, Amanda, Zetterberg, Henrik, Schott, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131984/
https://ncbi.nlm.nih.gov/pubmed/30211292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.06.001
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