CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

BACKGROUND: Increased CSF levels of a number of synaptic markers have been reported in Alzheimer’s disease (AD), but little is known about their concentrations in frontotemporal dementia (FTD). We investigated this in three synaptic proteins, neurogranin, SNAP-25, and synaptotagmin-1. METHODS: CSF s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Alzheimers Res Ther
Main Authors: Clarke, Mica T. M., Brinkmalm, Ann, Foiani, Martha S., Woollacott, Ione O. C., Heller, Carolin, Heslegrave, Amanda, Keshavan, Ashvini, Fox, Nick C., Schott, Jonathan M., Warren, Jason D., Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918699/
https://ncbi.nlm.nih.gov/pubmed/31847891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0564-2
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