Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension

Advanced fibrosis and portal hypertension influence short-term mortality. Lipocalin 2 (LCN2) regulates infection response and increases in liver injury. We explored the role of intrahepatic LCN2 in human alcoholic hepatitis (AH) with advanced fibrosis and portal hypertension and in experimental mous...

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Udgivet i:Sci Rep
Main Authors: Chen, Jiegen, Argemi, Josepmaria, Odena, Gemma, Xu, Ming-Jiang, Cai, Yan, Massey, Veronica, Parrish, Austin, Vadigepalli, Rajanikanth, Altamirano, Jose, Cabezas, Joaquin, Gines, Pere, Caballeria, Juan, Snider, Natasha, Sancho-Bru, Pau, Akira, Shizuo, Rusyn, Ivan, Gao, Bin, Bataller, Ramon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7512007/
https://ncbi.nlm.nih.gov/pubmed/32968110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72172-7
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