Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis

OBJECTIVE: Alcoholic hepatitis (AH) is often associated with advanced fibrosis, which negatively impacts survival. We aimed at identifying kinases deregulated in livers from patients with AH and advanced fibrosis in order to discover novel molecular targets. DESIGN: Extensive phosphoprotein analysis...

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Publicado no:Gut
Main Authors: Morales-Ibanez, Oriol, Affò, Silvia, Rodrigo-Torres, Daniel, Blaya, Delia, Millán, Cristina, Coll, Mar, Perea, Luis, Odena, Gemma, Knorpp, Thomas, Templin, Markus F, Moreno, Montserrat, Altamirano, José, Miquel, Rosa, Arroyo, Vicente, Ginès, Pere, Caballería, Juan, Sancho-Bru, Pau, Bataller, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524790/
https://ncbi.nlm.nih.gov/pubmed/25652085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307979
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