Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis

OBJECTIVE: Alcoholic hepatitis (AH) is often associated with advanced fibrosis, which negatively impacts survival. We aimed at identifying kinases deregulated in livers from patients with AH and advanced fibrosis in order to discover novel molecular targets. DESIGN: Extensive phosphoprotein analysis...

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Bibliografiske detaljer
Udgivet i:Gut
Main Authors: Morales-Ibanez, Oriol, Affò, Silvia, Rodrigo-Torres, Daniel, Blaya, Delia, Millán, Cristina, Coll, Mar, Perea, Luis, Odena, Gemma, Knorpp, Thomas, Templin, Markus F, Moreno, Montserrat, Altamirano, José, Miquel, Rosa, Arroyo, Vicente, Ginès, Pere, Caballería, Juan, Sancho-Bru, Pau, Bataller, Ramon
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524790/
https://ncbi.nlm.nih.gov/pubmed/25652085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307979
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