Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis

OBJECTIVE: Alcoholic hepatitis (AH) is often associated with advanced fibrosis, which negatively impacts survival. We aimed at identifying kinases deregulated in livers from patients with AH and advanced fibrosis in order to discover novel molecular targets. DESIGN: Extensive phosphoprotein analysis...

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Publicat a:Gut
Autors principals: Morales-Ibanez, Oriol, Affò, Silvia, Rodrigo-Torres, Daniel, Blaya, Delia, Millán, Cristina, Coll, Mar, Perea, Luis, Odena, Gemma, Knorpp, Thomas, Templin, Markus F, Moreno, Montserrat, Altamirano, José, Miquel, Rosa, Arroyo, Vicente, Ginès, Pere, Caballería, Juan, Sancho-Bru, Pau, Bataller, Ramon
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524790/
https://ncbi.nlm.nih.gov/pubmed/25652085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307979
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