LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there are no effective therapies. Patients with AH show impaired hepatocyte proliferation, expansion of inefficient ductular cells and high lipopolysaccharide (LPS) levels. It is unknown whether LPS mediates ductul...

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Vydáno v:Sci Rep
Hlavní autoři: Odena, Gemma, Chen, Jiegen, Lozano, Juan Jose, Altamirano, Jose, Rodrigo-Torres, Daniel, Affo, Silvia, Morales-Ibanez, Oriol, Matsushita, Hiroshi, Zou, Jian, Dumitru, Raluca, Caballeria, Juan, Gines, Pere, Arroyo, Vicente, You, Min, Rautou, Pierre-Emmanuel, Valla, Dominique, Crews, Fulton, Seki, Ekihiro, Sancho-Bru, Pau, Bataller, Ramon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067590/
https://ncbi.nlm.nih.gov/pubmed/27752144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35610
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