LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis

Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there are no effective therapies. Patients with AH show impaired hepatocyte proliferation, expansion of inefficient ductular cells and high lipopolysaccharide (LPS) levels. It is unknown whether LPS mediates ductul...

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Publicado no:Sci Rep
Main Authors: Odena, Gemma, Chen, Jiegen, Lozano, Juan Jose, Altamirano, Jose, Rodrigo-Torres, Daniel, Affo, Silvia, Morales-Ibanez, Oriol, Matsushita, Hiroshi, Zou, Jian, Dumitru, Raluca, Caballeria, Juan, Gines, Pere, Arroyo, Vicente, You, Min, Rautou, Pierre-Emmanuel, Valla, Dominique, Crews, Fulton, Seki, Ekihiro, Sancho-Bru, Pau, Bataller, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067590/
https://ncbi.nlm.nih.gov/pubmed/27752144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35610
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