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Mesenchymal Stem Cells Inhibit Cutaneous Radiation-Induced Fibrosis by Suppressing Chronic Inflammation

Exposure to ionizing radiation (IR) can result in the development of cutaneous fibrosis, for which few therapeutic options exist. We tested the hypothesis that bone marrow-derived mesenchymal stem cells (BMSC) would favorably alter the progression of IR-induced fibrosis. We found that a systemic inf...

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Pubblicato in:Stem Cells
Autori principali: Horton, Jason A., Hudak, Kathryn E., Chung, Eun Joo, White, Ayla O., Scroggins, Bradley T., Burkeen, Jeffrey F., Citrin, Deborah E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511998/
https://ncbi.nlm.nih.gov/pubmed/23897677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1483
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