Differential gene expression of tumor-infiltrating CD8(+) T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

BACKGROUND: Cytotoxic CD8(+) T cell-mediated response is the most important arm of adaptive immunity, which dictates the capacity of the host immune response in eradicating tumor cells. Due to tumor intrinsic and/or extrinsic factors, the density and function of CD8(+) tumor-infiltrating lymphocytes...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Saleh, Reem, Sasidharan Nair, Varun, Toor, Salman M, Taha, Rowaida Z, Murshed, Khaled, Al-Dhaheri, Mahmood, Khawar, Mahwish, Petkar, Mahir Abdulla, Abu Nada, Mohamed, Al-Ejeh, Fares, Elkord, Eyad
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511623/
https://ncbi.nlm.nih.gov/pubmed/32948653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001294
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