Immune Checkpoints in Circulating and Tumor-Infiltrating CD4(+) T Cell Subsets in Colorectal Cancer Patients

Blockade of inhibitory immune checkpoints (ICs) is a promising therapeutic approach; however, it has shown limited success in some cancers including colorectal cancer (CRC). The tumor microenvironment (TME) is largely responsible for response to therapy, and its constituents may provide robust bioma...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Toor, Salman M., Murshed, Khaled, Al-Dhaheri, Mahmood, Khawar, Mahwish, Abu Nada, Mohamed, Elkord, Eyad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928042/
https://ncbi.nlm.nih.gov/pubmed/31921188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02936
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