Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma

Chimeric antigen receptor (CAR) therapy is a promising immunotherapeutic strategy for treating multiple refractory blood cancers, but further advances are required for solid tumor CAR therapy. One challenge is identifying a safe and effective tumor antigen. Here, we devise a strategy for targeting h...

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Udgivet i:Nat Commun
Main Authors: Tseng, Hsiang-chi, Xiong, Wei, Badeti, Saiaditya, Yang, Yan, Ma, Minh, Liu, Ting, Ramos, Carlos A., Dotti, Gianpietro, Fritzky, Luke, Jiang, Jie-gen, Yi, Qing, Guarrera, James, Zong, Wei-Xing, Liu, Chen, Liu, Dongfang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511348/
https://ncbi.nlm.nih.gov/pubmed/32968061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18444-2
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