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Development of a Novel Human CD147 Transgenic NSG Mouse Model to test SARS-CoV-2 Infection and Immune Responses

An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the newly emerged, rapidly spreading SARS-CoV-2 and development of therapeutic strategies. Studies show that the spike (S) proteins of SARS-CoV (SARS-CoV-S-1-S) and SARS-CoV-2 (SARS-CoV-2-S) bind to human...

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Detalhes bibliográficos
Publicado no:Res Sq
Main Authors: Badeti, Saiaditya, Tseng, Hsiang-chi, Romanienko, Peter, Yehia, Ghassan, Liu, Dongfang
Formato: Artigo
Idioma:Inglês
Publicado em: American Journal Experts 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8043462/
https://ncbi.nlm.nih.gov/pubmed/33851148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21203/rs.3.rs-396257/v1
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