Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects

Development of specific antiviral agents is an urgent unmet need for SARS-coronavirus 2 (SARS-CoV-2) infection. This study focuses on host proteases that proteolytically activate the SARS-CoV-2 spike protein, critical for its fusion after binding to angiotensin-converting enzyme 2 (ACE2), as antivir...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Cheng, Ya-Wen, Chao, Tai-Ling, Li, Chiao-Ling, Chiu, Mu-Fan, Kao, Han-Chieh, Wang, Sheng-Han, Pang, Yu-Hao, Lin, Chih-Hui, Tsai, Ya-Min, Lee, Wen-Hau, Tao, Mi-Hua, Ho, Tung-Ching, Wu, Ping-Yi, Jang, Li-Ting, Chen, Pei-Jer, Chang, Sui-Yuan, Yeh, Shiou-Hwei
Format: Artigo
Idioma:Inglês
Publicat: The Authors. 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510585/
https://ncbi.nlm.nih.gov/pubmed/33007239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108254
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars