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Furin cleavage of the Moloney murine leukemia virus Env precursor reorganizes the spike structure
The trimeric Moloney murine leukemia virus Env protein matures by two proteolytic cleavages. First, furin cleaves the Env precursor into the surface (SU) and transmembrane (TM) subunits in the cell and then the viral protease cleaves the R-peptide from TM in new virus. Here we analyzed the structure...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000802/ https://ncbi.nlm.nih.gov/pubmed/24711391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317972111 |
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