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Maturation cleavage of the murine leukemia virus Env precursor separates the transmembrane subunits to prime it for receptor triggering

The Env protein of murine leukemia virus matures by two cleavage events. First, cellular furin separates the receptor binding surface (SU) subunit from the fusion-active transmembrane (TM) subunit and then, in the newly assembled particle, the viral protease removes a 16-residue peptide, the R-pepti...

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Detalhes bibliográficos
Main Authors: Löving, Robin, Wu, Shang-Rung, Sjöberg, Mathilda, Lindqvist, Birgitta, Garoff, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356626/
https://ncbi.nlm.nih.gov/pubmed/22547812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118125109
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