ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems

BACKGROUND: Many favorable traits of crops and livestock and human genetic diseases arise from multiple single nucleotide polymorphisms or multiple point mutations with heterogeneous base substitutions at the same locus. Current cytosine or adenine base editors can only accomplish C-to-T (G-to-A) or...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Xie, Jingke, Huang, Xingyun, Wang, Xia, Gou, Shixue, Liang, Yanhui, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Zhang, Quanjun, Ge, Weikai, Jin, Qin, Shi, Hui, Zhuang, Zhenpeng, Zhao, Xiaozhu, Lian, Meng, Wang, Jiaowei, Ye, Yinghua, Quan, Longquan, Wu, Han, Wang, Kepin, Lai, Liangxue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510086/
https://ncbi.nlm.nih.gov/pubmed/32967664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00866-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados