XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer

Pig cloning by somatic cell nuclear transfer (SCNT) remains extremely inefficient, and many cloned embryos undergo abnormal development. Here, by profiling transcriptome expression, we observed dysregulated chromosome-wide gene expression in every chromosome and identified a considerable number of g...

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Publicado no:Stem Cell Reports
Main Authors: Ruan, Degong, Peng, Jiangyun, Wang, Xiaoshan, Ouyang, Zhen, Zou, Qingjian, Yang, Yi, Chen, Fangbing, Ge, Weikai, Wu, Han, Liu, Zhaoming, Zhao, Yu, Zhao, Bentian, Zhang, Quanjun, Lai, Chengdan, Fan, Nana, Zhou, Zhiwei, Liu, Qishuai, Li, Nan, Jin, Qin, Shi, Hui, Xie, Jingke, Song, Hong, Yang, Xiaoyu, Chen, Jiekai, Wang, Kepin, Li, Xiaoping, Lai, Liangxue
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830944/
https://ncbi.nlm.nih.gov/pubmed/29337117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.12.015
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