ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems

BACKGROUND: Many favorable traits of crops and livestock and human genetic diseases arise from multiple single nucleotide polymorphisms or multiple point mutations with heterogeneous base substitutions at the same locus. Current cytosine or adenine base editors can only accomplish C-to-T (G-to-A) or...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:BMC Biol
Hlavní autoři: Xie, Jingke, Huang, Xingyun, Wang, Xia, Gou, Shixue, Liang, Yanhui, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Zhang, Quanjun, Ge, Weikai, Jin, Qin, Shi, Hui, Zhuang, Zhenpeng, Zhao, Xiaozhu, Lian, Meng, Wang, Jiaowei, Ye, Yinghua, Quan, Longquan, Wu, Han, Wang, Kepin, Lai, Liangxue
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510086/
https://ncbi.nlm.nih.gov/pubmed/32967664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00866-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky